pentobarbital will lessen the extent or outcome of capivasertib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Robust or moderate CYP3A inducers reduce capivasertib exposure, which may lower efficacy.pentobarbital will decrease the extent or effect of bortezomib by impacting hepatic/intestinal enzyme CYP3A4… Read More